THE SISTERS BROTHERS revolves around the colorfully named gold prospector Hermann Kermit Warm who's being pursued across 1000 miles of 1850's Oregon desert to San Francisco. The notorius assassins, Eli and Charlie Sisters have been hired to kill the prospector who has stolen from their boss. Except Eli is having a personal crisis and beginning to doubt the longevity of his chosen career, and Hermann might have a better offer. The film stars John C. Reilly, Joaquin Phoenix and Jake Gyllenhaul.
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